Reishi: A Mighty Medicinal Mushroom
Sunday, January 22, 2012
Science has taught us that mushrooms can be far more than a tasty pizza topping or a meaty stir-fry ingredient. While it has long been known that mushrooms possess medicinal properties, current research has identified active chemical constituents and assessed their effectiveness in treating various medical conditions.
The reishi mushroom (Ganoderma lucidum) has been used in traditional Chinese medicine for thousands of years. Harvested from decaying logs and tree stumps in the coastal provinces of China, reishi, or ling zhi, is highly prized as an elixir of immortality. The royalty of ancient China used it in their quest for immortality and to promote calmness. Sixteenth century Chinese practitioners utilized it to affect the life energy (qi) of the heart, treat ailments of the chest, increase intellectual capacity, and improve memory.
Purported uses of reishi mushrooms include hypertension, high cholesterol, viral infections, liver disorders, and immune modulation. What is it about reishi mushrooms that makes them so useful medicinally? The answer lies in the mushroom’s active chemical constituents:
§ Triterpenes. The triterpenes, which include ganodermic acids, are reported to have antihypertensive effects. Studies indicate that reishi’s triterpenes may reduce blood pressure in two ways: 1) by acting on the central nervous system, and 2) by inhibiting angiotensin converting enzyme (like a pharmaceutical ACE inhibitor) to promote vasodilation. Triterpenes are also thought to be responsible for lowering cholesterol levels by acting on 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA), the key enzyme involved in making cholesterol.
§ Polysaccharides. Reishi’s polysaccharides, such as beta glucans, have been shown to stimulate the activity of immune cells (such as macrophages) and increase the levels of protective substances (such as TNF and interleukins) that they produce. Such actions make reishi an effective treatment for viral infections such as influenza, HIV, herpes simplex, and Epstein-Barr virus. In addition, in vitro studies have found that reishi’s polysaccharides inhibit tumor cell growth. Polysaccharides isolated from reishi are also attributed to improvements in liver function, as indicated by decreases in serum liver enzymes: aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase. The studies also revealed decreased total bilirubin and liver collagen content.
§ Adenosine. The high levels of adenosine in reishi are thought responsible for inhibiting platelet aggregation, which may make the mushroom a potential therapy for coronary heart disease treatment and prevention.
Reishi’s cancer-fighting capabilities continue to be a key area of scientific research. Small clinical studies using reishi reveal increased antioxidant activity and immune responses in patients with advanced disease. Furthermore, reishi shows great potential as a supportive treatment for patients undergoing chemotherapy: In vitro and animal studies indicate that reishi increases the sensitivity of cancer cells to chemotherapy, alleviates chemotherapy-induced nausea, and prevents chemotherapy-induced nephrotoxicity.
The benefits don’t stop there! Nutritionally, reishi mushrooms are great sources of selenium, iron, protein, and dietary fiber. Now that’s a mighty mushroom!
Karen Brothers, ND student, NCNM
To learn more about reishi mushrooms, check out these references:
§ Gaby, Alan R. and Healthnotes, Inc. The Natural Pharmacy. New York: Three Rivers Press, 2006.
§ Murray, Michael, Pizzorno, Joseph, and Pizzorno, Lara. The Encyclopedia of Healing Foods. New York: Atria Books, 2005.
§ Natural Standard Database, “Reishi mushroom (Ganoderma lucidum)”
Labels: health benefits, ling zi, mushrooms, reishi
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Formulas makes no representations as to accuracy, completeness, suitability, or validity of any information on this blog and will not be liable for the content. All information is provided on an as-is basis.
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15 Comments :
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Medicinal mushrooms are, indeed, proven to help cure cancer. It has the ability of suppressing back the growth of cancer cells. Researchers also found evidence that mushrooms stops the activity of enzyme that may stimulate the growth of cancer cells and the expansion of blood vessels that are known to be crucial for the survival of any cancer cell.
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